Original Reporting

Different viruses, different questions: Lessons from California’s 2025–2026 respiratory virus season

A year of online conversation about flu, COVID-19, and RSV immunizations across California found that each vaccine generated distinct conversations. Differences in lived experience, perceived risk, and trust shape how people think about them, meaning combined messaging may miss what matters most.

The story

The story: why vaccine uptake remains low

COVID-19, influenza (flu), and respiratory syncytial virus (RSV) cause millions of illnesses in the United States each year, leading to thousands of hospitalizations and deaths.

Despite evidence that immunization reduces the risk of severe illness, hospitalization, and death, uptake remains low across all three diseases. During the 2025–2026 season, fewer than half of adults received a flu vaccine, and only 17.5 percent received a COVID-19 vaccine. RSV protection among eligible infants was higher, with 65.1 percent protected through either maternal vaccination or preventive antibody immunization. Among adults, RSV vaccine uptake reached 43.2 percent for those ages 75 and older and 32.8 percent for adults ages 50–74 with a high-risk condition.

Conversation spikes

What drove online conversation about flu, COVID-19, and RSV in California?

The three respiratory viruses generated different conversation patterns throughout the year. Select the buttons below to explore the patterns for each virus.

Flu vaccines

Flu conversation followed a seasonal pattern, with peaks driven by local disease severity and changes to federal guidance

Conversation about flu vaccines followed a clear seasonal pattern that closely aligned with the respiratory virus season. Discussion was elevated from January through mid-March, declining during the summer months, and began increasing again in August.

Overall conversation volume throughout the year (132,000 mentions) was substantially lower than for COVID-19 vaccines, but higher than for RSV immunizations.

Peaks in conversation were driven primarily by California-specific events, including seasonal vaccination campaigns, regional public health recommendations, and reports of local flu cases and deaths. The trendline below highlights the primary drivers of these increases.

Online mentions of flu, COVID-19, and RSV immunizations in 2025

Select a number on the trendline to see what drove conversation.

Scroll the chart sideways to see the full year.

Flu vaccines: conversation peaks

Local media warned of a severe flu season with approximately 900 deaths reported, including a pediatric death in San Diego County. Nationally, CDC officials faced criticism for attending a WHO meeting on flu vaccines amid an executive order and the cancellation of an FDA meeting on the 2025–2026 flu vaccine.
Monthly online mentions of flu, COVID-19, and RSV in California
MonthFluCOVID-19RSV

Source: Infodemiology.com analysis, 2026. Note: Weekly online mentions of flu, COVID-19, or RSV in California during 2025 include social and digital media, online video platforms, news sites, blogs, forums, Q&A sites, and other web-based sources. Several posts mention more than one vaccine and are counted once for each vaccine they reference. All three viruses share one vertical scale so volumes can be compared directly; because COVID-19 conversation was roughly six times the volume of flu conversation, the flu and RSV lines sit low on the axis.

Public perceptions

How does the public perceive each vaccine?

Underlying concerns and beliefs about each vaccine differed. Flu conversations centered on vaccine efficacy, with questions about whether the vaccine actually worked. COVID-19 conversations were dominated by safety doubts and institutional distrust. RSV generated lower overall discussion but also showed strong public recognition that the disease poses a serious risk to infants and older adults. Select the buttons below to learn more about public perceptions.

Flu vaccines

Concerns about effectiveness were driven by anecdotes about illness after vaccination and low perceived risk

Flu vaccine conversation was dominated by concerns about effectiveness. Many people appeared to judge the flu vaccine by whether it prevents infection, with limited recognition that its primary benefit is reducing severe illness, hospitalization, and death. Closely tied to these discussions was the persistent misconception that the flu vaccine causes the flu.

Perceptions that the vaccine offers limited value—or can make people sick—were driven by anecdotal accounts of illness following vaccination, widespread misinterpretation of a study on vaccine efficacy, concerns about vaccine strain mismatches, and the false belief that the inactivated virus used in the vaccine can cause infection. These narratives often coincided with a preference for natural immunity or alternative prevention measures, supported by low perceived risk from influenza, skepticism about media coverage of flu cases and deaths, and low confidence in vaccine effectiveness.

Safety concerns extended beyond flu-specific claims

Safety and ingredient concerns were also common. Some questioned vaccine ingredients or raised concerns about side effects. While many of these narratives focused on flu-specific claims—such as concerns about Guillain-Barré syndrome or allegations that the vaccine contains harmful ingredients like mercury—others borrowed claims more commonly associated with COVID-19 vaccines, including myocarditis and cancer. These cross-vaccine narratives were most common when flu and COVID-19 vaccines were promoted together, but also appeared in discussions of flu vaccination alone.

Recognition of disease severity and protecting vulnerable groups drove support

Supportive flu vaccine narratives were often grounded in firsthand experience with the flu and recognition of its potential severity. People described prolonged illness or serious complications, and many emphasized protecting vulnerable groups, including young children, older adults, and those with chronic illnesses. These discussions suggest that messaging focused on disease severity and protection of others may be more persuasive than messaging centered on personal risk reduction.

Health messaging

How California’s respiratory virus messaging aligned—and conflicted—with public conversation

Comparing official messaging with public conversation highlights where messaging aligned with public concerns and where important gaps remained. Select a finding to see detailed insights and what they mean.

Bundling vaccines may simplify communication, but can also blur how people interpret each vaccine

Messaging about respiratory viruses from health entities and government pages focused most on flu vaccines, often promoting the vaccine on its own (46 percent of posts). However, communications also frequently promoted COVID-19 vaccines alongside flu vaccines (21 percent), or promoted flu, COVID-19, and RSV immunizations together (19 percent). The chart below shows the types of vaccines discussed in health entity messages.

Rarely did messaging promote RSV or COVID-19 immunizations on their own (7 percent and 3 percent, respectively). Most messaging that promoted RSV immunization also promoted both flu and COVID-19 vaccines.

While bundling respiratory virus immunizations reflects common public health communication practices, our analysis suggests it can blur important differences in how people perceive each immunization.

As shown throughout this report, promoting vaccines together can also allow concerns about one vaccine to spill over into conversations about the others.

Vaccines discussed in health entity messaging

Share of messaging by the vaccine or vaccines promoted.

Flu only
46%
COVID and flu
21%
COVID, flu, and RSV
19%
RSV only
7%
COVID only
3%
Flu and RSV
2%
Respiratory viruses generally
2%
COVID and RSV
<0.5%

Source: Infodemiology.com analysis, 2026. Note: Analysis of health entity and government page messaging is limited to Facebook.

Takeaways

What do the patterns suggest for communicators preparing for respiratory virus season?

As communicators prepare for the 2026–2027 respiratory virus season, this analysis highlights several strategies to strengthen messaging about COVID-19, flu, and RSV immunization. Although this report focuses on California, many of the observed themes mirror national trends and may be relevant to communicators across the United States. Select a takeaway below to view the full recommendation.

Co-administration remains an important strategy for improving uptake, and many respiratory virus immunizations are recommended during the same period. However, increasing standalone communications for each immunization may better address the specific questions, concerns, and motivations associated with each virus while reducing the spillover of hesitancy from one vaccine to another. This is particularly important for RSV, which was often discussed only in the context of flu and COVID-19 rather than on its own.

Confusion about eligibility and access increased following changes to federal recommendations, but many questions extended beyond those policy announcements. Clear, consistent messaging about who is eligible, where immunizations are available, and what current recommendations are—distributed through both owned channels and partners—can help reduce confusion before it spreads.

Trust varies widely across audiences, making messenger selection as important as message content. Health systems, health care professionals, and local health departments remain important sources for many people. At the same time, personal stories from community members can help reach audiences who are skeptical of government institutions or traditional public health messaging.

Tailor messages to how different audiences experience respiratory viruses. People evaluated the need for vaccination through the lens of their own experiences and risk, which often differed by virus and stage of life. Messaging that acknowledges those experiences while emphasizing benefits that resonate with specific audiences—such as protecting vulnerable family members, reducing illness severity, or preventing long-term complications—may be more persuasive than messages focused solely on severe outcomes. Because RSV was widely recognized as a serious illness, messages emphasizing protection of infants and older adults may be particularly effective.

Many safety and effectiveness concerns about flu and COVID-19 vaccines appeared to reflect firmly held beliefs rather than genuine information seeking. Communicators should prioritize responding to legitimate questions, particularly in the comment sections of owned content, where clear, evidence-based answers can build trust. Broadly engaging with entrenched narratives may reinforce existing beliefs or draw additional attention to myths without reaching audiences who remain open to vaccination.